
These approved products are only available with a prescription from a licensed healthcare provider. While THC has the what is alcoholism potential to lead to addiction, there are no documented cases of individuals experiencing CBD addiction or CBD withdrawal. This is likely due to the different mechanisms in the brain that are impacted by cannabinoid use and how the body processes these specific compounds. Note that people taking the prescription drug Epidiolex — a pure CBD isolate extract — should not stop taking it abruptly.
- That said, some potential side effects of taking CBD exist, and the risks aren’t fully known.
- Therefore, the versatile pharmacological profile and safety of CBD support its therapeutic potential in the management of SUD.
- They explored the activation of MAPK pathway and its downstream pathways that regulate the expression of the transcriptional (CREB) and neurotrophic (BDNF) factors, responsible for the levels of neuronal hippocampal proliferation.
- The rate at which tolerance develops can also differ based on individual factors such as metabolism, frequency of use, and the method of administration.
- Your Cannabiva product is triple-tested — immediately after harvest, following extraction, and in finished product form — to ensure it is 100% free from pesticides, harmful chemicals, and heavy metals.
- In fact, some evidence indicates it may have some benefits for helping to treat addiction.
The evidence for cannabidiol health benefits

To keep things simple, we’ll define addiction as someone becoming reliant on something, and its use impacts their daily life in more than one negative way. That reliance could be physical or emotional, with both being valid situations. There are a variety of different types of addictions, with some people becoming addicted to substances and other people experiencing process addictions. Cannabidiol (CBD) has become extremely popular for health and wellness in the past few years. As more and more people try CBD for the first time, they may be introduced to various potential benefits. One interesting thing about CBD is that many people use it to find relief from multiple symptoms, so it’s a comprehensive and holistic option for various health goals.
Cannabidiol used in addiction medicine
In fact, according to a 2023 Healthline survey, 25% of adults in the United States have tried or are interested in trying CBD products. By now, you may’ve heard someone mention CBD, especially if you live with a chronic condition like pain or anxiety. For multiple sclerosis, a report published in “Frontiers in Neurology” cited CBD’s potential in reducing fatigue, pain, and spasticity while improving mobility. Cannabidiol, more commonly known as CBD, has gained significant attention in recent years. Despite its widespread use and recognition, understanding what CBD is and how it works is crucial for its safe and is cannabidiol addictive effective use. When a product is in violation of the FD&C Act, FDA considers many factors in deciding whether or not to initiate an enforcement action.

Are you missing these signs of anxiety or depression?
Interestingly, the results reported by our group in an animal model of spontaneous cannabinoid withdrawal support the implementation of randomized controlled trials (RCT) using only CBD. In addition, variables like motivation, reinforcement, withdrawal, relapse, and retention in treatment should be considered for a global overview during treatment for CUD. Smoking is another SUD in which clinical studies were predominantly conducted to evaluate CBD actions. Nevertheless, more information is required to accurately assess the therapeutic role that CBD could have in smoking cessation. Several studies in animals and humans demonstrated the absence of rewarding properties (Parker et al., 2004; Katsidoni et al., 2013; Babalonis et al., 2017; Schoedel et al., 2018). Indeed, recent studies carried out in mice in our laboratory further demonstrate that CBD is not an addictive substance.

CBD: Is it addictive?
Also, it covers all the mechanisms proposed to mediate the CBD actions on drug addiction. Cue-induced craving and anxiety in heroin-abstinent individuals were decreased by acute CBD administration (400 or 800 mg), further demonstrating efficacy for CBD in ameliorating clinical signs and symptoms critical to the continued cycle of addiction. Additionally, there was a prolonged impact on these measures one week after short-term repeated CBD treatment. CBD also reduced physiological measures of stress reactivity, such as increased heart rate and cortisol levels, induced by salient drug cues without impacting cognition (Hurd et al., 2019) (Table 2).
What is the difference between CBD and CBN?
To understand if CBD is addictive, we need to consider how it interacts with the brain. Unlike THC, which binds directly with the CB1 receptors in the brain to produce a euphoric effect, CBD interacts differently with the endocannabinoid system (ECS). CBD prevents the breakdown of a =https://ecosoberhouse.com/ compound called anandamide, which helps regulate functions like sleep, pain, and immune-system responses. By enhancing anandamide’s availability, CBD helps to naturally balance the ECS without causing psychoactive effects. CBD’s ability to interact with multiple systems in the body has made it a subject of interest for numerous therapeutic applications, from pain management and anxiety reduction to potential uses in addiction treatment and neurodegenerative disorders. Recovery Ranch PA offers a comprehensive range of addiction treatment services.
- It’s crucial to underscore that CBD online products is not an addictive nor mind-altering substance, since it has a low affinity to cannabinoid receptors within the body, thus producing only mild effects.
- One interesting thing about CBD is that many people use it to find relief from multiple symptoms, so it’s a comprehensive and holistic option for various health goals.
- In this regard, it is relevant to emphasize that according to the multiple pharmacological profile of CBD accounting for the anxiolytic, antidepressant or antipsychotic properties, comorbid clinical entities such as anxiety, depression or psychotic disorders could be also successfully managed.
- ECS regulates several physiological functions and mediates the crosstalk between different neurotransmitter systems, therefore, representing a key player in the control of behavioral responses (Katona and Freund, 2012; Atkinson and Abbott, 2018).
- Only high doses of the cannabinoid THC have the proven potential to cause withdrawal effects.

While there is still more research to be done into long-term effects, it is important that we consider CBD separately from the side effects of marijuana and its reputation. A study published in Addictive Behaviors showed that it could be a potent treatment option for nicotine addiction. CUD typically results when individuals use products high in THC, meaning it’s not usually a concern for individuals who solely use CBD. While this is true, it’s important to keep an eye on any symptoms you may be experiencing and be honest with yourself. If you think CBD isn’t the right choice for you, you most likely won’t encounter any significant adverse effects by stopping use.